Protecting Group-Free Glycosylations
Author(s): Dr. S.K. Mishra
Publication #: 2205012
Date of Publication: 11.09.2022
Country: India
Pages: 1-12
Published In: Volume 8 Issue 5 September-2022
Abstract
Oligosaccharide derivatives, particularly glycosylated oligosaccharides, are important compounds in living systems, exhibiting multifunctional characteristics in various kinds of life phenomena. The development of an efficient synthetic method is demanded to supply sufficient quantities of oligosaccharide-glycomaterials for basic research. Although many chemical or chemo-enzymatic processes for constructing glycosidic bonds have resulted from rapid advances in modern organic synthesis and biotechnology, these processes involve the use of protecting groups. This review presents an overview of recent advances in protecting group-free chemical and chemo-enzymatic processes for synthesis of oligosaccharide-glycosides.
Keywords: oligosaccharide, protecting group-free glycosylation, sugar epoxide, sugar oxazoline
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