Nanoparticle Synthesis, Characterization and Its Applications in Cancer Drug Delivery- A Review
Author(s): Malarvizhi T.
Publication #: IJIRCT1201028
Date of Publication: 13.08.2015
Country: India
Pages: 117-123
Published In: Volume 1 Issue 1 August-2015
Abstract
Cancers are a large family of diseases that involve abnormal cell growth with the potential to invade or spread to other parts of the body. Variety of treatments have been developed and optimized for reducing their adverse effects and as a step for their cure. Major research is being carried out throughout the world for improvising existing treatments as well as developing new ones. Over the years, chemotherapy remains to be the most effective treatment available. As the painful aspect of chemotherapy is well known, researchers are now focusing on alleviating these side effects. Targeted drug delivery is considered more beneficial for this kind of treatment. In this context, Nanofibers offer numerous advantages, most notably high surface area, small pore size and high pore volume. These characteristics led to their exploitation in many innovative applications including drug delivery, wound healing, scaffold preparation, fuel cells etc. This review paper briefly deals with the nanoparticle preparation techniques, characterization, cytotoxicity assay and drug release kinetics and some of its applications.
Keywords: chemotherapy, nanoparticles, drug delivery, drug release kinetics
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