Brassinolide-Mediated Stress Management: Multifaceted Approach to Plant Protection

Author(s): Harshita Saini, Suresh Chand Mali, Anita Dhaka, Sheetal Sharma, Rohini Trivedi

Publication #: 2601010

Date of Publication: 12.01.2026

Country: India

Pages: 1-12

Published In: Volume 12 Issue 1 January-2026

Abstract

Plants are constantly challenged by a variety of phytopathogens, including fungi, bacteria, and viruses, which can significantly impact crop productivity. To counter these biotic stresses, plants have evolved a complex innate immune system that involves both preformed barriers and inducible defence mechanisms. Brassinolide (BL), a bioactive brassinosteroid (BR), has emerged as a key regulator in enhancing plant immunity. Recent advances in plant physiology and molecular biology have shown that BL modulates defence responses by inducing the expression of pathogenesis-related genes, promoting the biosynthesis of antimicrobial compounds, and strengthening structural barriers, such as cell walls. Additionally, BL interacts synergistically or antagonistically with other phytohormones such as salicylic acid, jasmonic acid, and ethylene to fine-tune the immune response depending on the type of invading pathogen. BL also boosts transient H2O2 accumulation and the activities of POD, APX, GST, and GPX (antioxidant system). This review consolidates current knowledge on BL-mediated defence signalling pathways and explores its potential application in integrated disease management strategies to reduce chemical pesticide usage and promote sustainable agriculture.

Keywords: Brassinolide, defence responses, pathogenesis-related genes, antioxidant system

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