Assessment of The Effect of Physical Factors on The Antimicrobial Activity of Solanum surattense (Burm. f.) Extract
Author(s): Nisha Suwalaka, Uttam Prakash Sharma
Publication #: 2512031
Date of Publication: 30.12.2025
Country: India
Pages: 1-6
Published In: Volume 11 Issue 6 December-2025
Abstract
Solanum surattense Burm. f., a medicinal plant widely used in traditional Indian medicine, exhibits diverse pharmacological properties, including antimicrobial activity. This study aimed to evaluate the effect of physical factors, temperature, pH, and light exposure, on the antimicrobial efficacy of its ethanolic plant extract (root, stem, and leaves). The extract was tested against four bacterial strains: Staphylococcus aureus, Escherichia coli, Salmonella typhi, and Shigella dysenteriae using the cup well method. The results indicated significant antibacterial activity, with S. aureus being the most susceptible (19.8 ± 0.7 mm ZOI). Temperature, extreme pH, and sunlight exposure significantly reduced activity, whereas low temperatures, neutral pH, and dark storage preserved efficacy. These findings highlight the sensitivity of bioactive compounds to environmental conditions and the need for optimal handling and storage. The study underscores the potential of S. surattense as a natural antimicrobial agent and provides a foundation for developing stable, plant-based therapeutic formulations.
Keywords: Antibacterial activity, Antifungal activity, Solanum surratance.
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