Comparative Efficacy of High-Flow Nasal Cannula versus Non-Invasive Ventilation in Acute Hypoxemic Respiratory Failure: A Quantitative Analysis

Author(s): Abdulkhaliq M. Alanazi, Salah B. Alanazi, Saad N. Alrashdaa, Nawaf A. Alnaam

Publication #: 2003005

Date of Publication: 05.05.2020

Country: Saudi Arabia

Pages: 15-20

Published In: Volume 6 Issue 3 May-2020

DOI: https://doi.org/https://doi.org/10.5281/zenodo.11910267

Abstract

This prospective randomized controlled trial compared the efficacy of High-Flow Nasal Cannula (HFNC) with Non-Invasive Ventilation (NIV) in 150 patients with acute hypoxemic respiratory failure in the Intensive Care Unit (ICU). While HFNC showed a trend towards higher treatment success and lower intubation rates compared to NIV, these differences were not statistically significant. ICU mortality rates were comparable between the two groups. These findings suggest that both HFNC and NIV are effective respiratory support modalities for managing acute hypoxemic respiratory failure, highlighting the need for individualized patient-centered respiratory care decisions.

Keywords: Acute Hypoxemic Respiratory Failure, High-Flow Nasal Cannula, Non-Invasive Ventilation, Intensive Care Unit, Respiratory Support, Treatment Success, Intubation, ICU Mortality

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